SGK1 抗体 (C-Term)
Quick Overview for SGK1 抗体 (C-Term) (ABIN783476)
抗原
See all SGK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects SGK1 / SGK at C-term. SGK1 antibody is predicted to not cross-react with other SGK protein family members.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the carboxy terminus of human SGK1
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anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-431) antibody
SGK1 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4D7-G3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer422) antibodySGK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 172-431) antibodySGK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer78) antibodySGK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 145-386) antibodySGK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 247-406) antibodySGK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pThr256) antibodySGK1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer422) antibodySGK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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别名
- SGK1 / SGK
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背景
- Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1.3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development. At least five isoforms of SGK1 are known to exist.Synonyms: Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1
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基因ID
- 6446
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NCBI登录号
- NP_001137148
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UniProt
- O00141
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途径
- MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
抗原
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