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SAA 抗体

SAA 适用: 人 WB, EIA, ELISA (Detection), ELISA (Capture) 宿主: 小鼠 Monoclonal B332A unconjugated
产品编号 ABIN782007
发货至: 中国
  • 抗原 See all SAA 抗体
    SAA (Serum Amyloid A (SAA))
    适用
    • 51
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    宿主
    • 44
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    小鼠
    克隆类型
    • 45
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    单克隆
    标记
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    This SAA antibody is un-conjugated
    应用范围
    • 48
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    Western Blotting (WB), Enzyme Immunoassay (EIA), ELISA (Detection), ELISA (Capture)
    特异性
    This antibody recognizes native and recombinant Human Serum Amyloid A (SAA).
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Human recombinant SAA, conjugated with carrier protein
    克隆位点
    B332A
    亚型
    IgG1
    Top Product
    Discover our top product SAA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    5.8 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    SAA (Serum Amyloid A (SAA))
    别名
    Serum Amyloid A Protein (SAA) (SAA 产品)
    别名
    PIG4 antibody, SAA antibody, SAA2 antibody, TP53I4 antibody, zgc:103580 antibody, saa antibody, SAA1 antibody, Saa-1 antibody, Saa2 antibody, serum amyloid A1 antibody, serum amyloid A antibody, serum amyloid A protein antibody, serum amyloid A-3 antibody, HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 antibody, serum amyloid A2 antibody, serum amyloid A 1 antibody, SAA1 antibody, saa antibody, LOC476879 antibody, SAA antibody, SAA3 antibody, HPS5 antibody, SAA2 antibody, Saa1 antibody, LOC100270725 antibody
    背景
    The Serum Amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2
    基因ID
    6288
    NCBI登录号
    NP_000322
    UniProt
    P02735
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