SGK1 抗体
Quick Overview for SGK1 抗体 (ABIN781842)
抗原
See all SGK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to SGK1.
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纯化方法
- Protein A chromatography
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免疫原
- SGK1 antibody was raised against recombinant protein
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亚型
- IgG1
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anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 172-431) antibody
SGK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-431) antibodySGK1 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4D7-G3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer422) antibodySGK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer78) antibodySGK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 145-386) antibodySGK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 247-406) antibodySGK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pThr256) antibodySGK1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer422) antibodySGK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0,49 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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别名
- SGK1 / SGK
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背景
- SGK, a SGK type protein kinase, is a multi-functional kinase that is phosphorylated and activated through a 3-phosphoinositide-dependent protein kinase 1 (PDK1) signaling pathway. The protein has been shown to activate certain potassium, sodium and chloride channels which function in cell survival, neuronal excitability and renal sodium excretion. SGK transcription can be stimulated by glucocorticoids, aldosterone, TGF-beta1, serum, increase of intracellular Ca2+ and phorbolesters, and can be downregulated by cAMP. At least 2 mRNA variants have been reported. The SGK1 gene has been mapped to chromosome 6q23, a region frequently affected by deletion in various human neoplasms, and has been shown to be upregulated in lung fibrosis, diabetic nephropathy and chronic viral hepatitis.Synonyms: Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1
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基因ID
- 6446
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NCBI登录号
- NP_001137148
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UniProt
- O00141
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途径
- MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
抗原
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