p53 抗体
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北京 101111
Quick Overview for p53 抗体 (ABIN781170)
抗原
See all p53 (TP53) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Nucleus
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纯化方法
- Protein G-Sepharose affinity purified.
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免疫原
- Recombinant fragment of Human TP53 (C-terminus).
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亚型
- IgG
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应用备注
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000 .
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 50µg/50µl
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缓冲液
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- p53 (TP53) (Tumor Protein P53 (TP53))
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别名
- TP53
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背景
- This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.
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分子量
- 50kDa
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NCBI登录号
- NM_000546
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途径
- p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
抗原
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