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Retinoblastoma Binding Protein 8 抗体 (AA 621-720)

This anti-Retinoblastoma Binding Protein 8 antibody is a 兔 多克隆 antibody detecting Retinoblastoma Binding Protein 8 in ELISA, WB, IHC (p), IHC (fro), IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN762956
发货至: 中国

Quick Overview for Retinoblastoma Binding Protein 8 抗体 (AA 621-720) (ABIN762956)

抗原

See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
Retinoblastoma Binding Protein 8 (RBBP8)

适用

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宿主

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克隆类型

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多克隆

标记

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This Retinoblastoma Binding Protein 8 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 621-720

    预测反应

    Human,Mouse,Rat,Pig,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CtIP/RBBP8

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Retinoblastoma Binding Protein 8 (RBBP8)

    别名

    Ctip

    背景

    Synonyms: COM1_HUMAN antibody CtBP interacting protein antibody CtBP-interacting protein antibody CtIP antibody DNA endonuclease RBBP8, RBBBP8, RBBP-8, RBBP8, Retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like, RIM, SAE2, Sporulation in the absence of SPO11 protein 2 homolog.

    Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

    基因ID

    5932

    途径

    Cell Division Cycle, DNA Damage Repair
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