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GRB2 抗体 (AA 1-217) (FITC)

This 兔 多克隆 antibody specifically detects GRB2 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7995399
发货至: 中国
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Room 801-803
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Quick Overview for GRB2 抗体 (AA 1-217) (FITC) (ABIN7995399)

抗原

See all GRB2 抗体
GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))

适用

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宿主

  • 87
  • 12
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克隆类型

  • 77
  • 24
  • 1
多克隆

标记

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This GRB2 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 19
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    AA 1-217

    原理

    Anti-GRB2 Antibody FITC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human < a href=https://www.bosterbio.com/anti-grb2-antibody-y209-a00351-boster.html style=color:#EA8D28>GRB2 recombinant protein (Position: M1-V217).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))

    别名

    GRB2

    背景

    Background: GRB2, Growth factor receptor-bound protein 2, is an adaptor protein involved in signal transduction/cell communication. The GRB2 gene encodes a protein that has homology to noncatalytic regions of the SRC oncogene product. Its two SH3 domains complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. In humans, the GRB2 protein is encoded by the GRB2 gene. Grb2 is widely expressed and is essential for multiple cellular functions. The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the sem-5 gene of Caenorhabditis elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: growth factor receptor bound protein 2

    基因ID

    2885

    UniProt

    P62993

    途径

    RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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