Retinoblastoma Binding Protein 8 抗体 (AA 620-897)
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Quick Overview for Retinoblastoma Binding Protein 8 抗体 (AA 620-897) (ABIN7938099)
抗原
See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 620-897
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原理
- CtIP antibody (mAb) (Clone 14-1)
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纯化方法
- Protein A Chromatography
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免疫原
- This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.
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亚型
- IgG1
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anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 452-747) antibody
RBBP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) antibodyRBBP8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 126-331) antibodyRBBP8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 1-300) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (Center) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) antibodyRBBP8 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro), EIA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (C-Term) antibodyRBBP8 适用: 人, Pig, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (pThr847) antibodyRBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (pSer327) antibodyRBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (pSer326) antibodyRBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1 - 2 μg/mL
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- Retinoblastoma Binding Protein 8 (RBBP8)
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别名
- CtIP
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背景
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Background_Plain: CtIP (CTBP interacting protein, RBBP8, RIM, COM1) is a transcriptional regulator and tumor suppressor first identified through its interaction with CTBP (C-Terminal Binding Protein). CtIP binds to the Rb protein and serves as a transcriptional repressor, through recruitment of CtBP and also by interaction with general transcription factors TFIID and TFIIB. CtIP also interacts with Rb-related protein p130 and Ikaros, a master regulator in lymphocyte development. CtIP is phosphorylated upon DNA damage (likely by ATM and/or ATR), interacts with BRCA1 and plays a critical role in facilitating DNA damage repair. Mutations that abolish the interaction between CtIP and BRCA1 result in loss of cell cycle control leading to the development of cancer.
Aliases: RBBP8, RIM, COM1, JWDS, SAE2, SCKL2
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分子量
- 120 kDa
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NCBI登录号
- NP_002885
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途径
- Cell Division Cycle, DNA Damage Repair
抗原
-
