STAT2 抗体 (pTyr690)
(1 reference)Quick Overview for STAT2 抗体 (pTyr690) (ABIN746183)
抗原
See all STAT2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr690
-
特异性
- This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat.
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Dog,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690
-
亚型
- IgG
-
-
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 151-250) antibody
STAT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 616-849) antibodySTAT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 587-838) antibodySTAT2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 742-851) antibodySTAT2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G7 unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibodySTAT2 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) antibodySTAT2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal STAT2-2650 unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) antibodySTAT2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 658-912) antibodySTAT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 571-851) antibodySTAT2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibodySTAT2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
-
: "JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
-
: "JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
-
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
-
别名
- Stat2
-
背景
-
Synonyms: P113, ISGF-3, STAT113, Signal transducer and activator of transcription 2, STAT2
Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
-
基因ID
- 6773
-
UniProt
- P52630
-
途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
抗原
-
