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STAT2 抗体 (C-Term)

STAT2 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855558
发货至: 中国
  • 抗原 See all STAT2 抗体
    STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
    抗原表位
    • 19
    • 16
    • 9
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    C-Term
    适用
    • 108
    • 44
    • 38
    • 3
    • 1
    • 1
    • 1
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    宿主
    • 112
    • 7
    • 1
    克隆类型
    • 102
    • 18
    多克隆
    标记
    • 60
    • 9
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    • 4
    • 4
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    This STAT2 antibody is un-conjugated
    应用范围
    • 98
    • 55
    • 41
    • 28
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    • 20
    • 11
    • 7
    • 7
    • 3
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    IP/MS validation was supported by references (PMID:30377386)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to STAT2 (signal transducer and activator of transcription 2, 113 kDa)
    STAT2 antibody [C2C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human STAT2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product STAT2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Jurkat , Raji , K562 , THP-1

    Validation: IP/MS, Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
    别名
    signal transducer and activator of transcription 2 (STAT2 产品)
    别名
    wu:fj84d07 antibody, p113 antibody, stat2 antibody, 1600010G07Rik antibody, AW496480 antibody, ISGF-3 antibody, P113 antibody, STAT113 antibody, signal transducer and activator of transcription 2 antibody, AGAP000099-PA antibody, stat2 antibody, STAT2 antibody, Stat2 antibody
    背景
    The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

    Cellular Localization: Cytoplasm , Nucleus
    分子量
    98 kDa
    基因ID
    6773
    UniProt
    P52630
    途径
    JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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