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Lamin A/C 抗体

The 小鼠 单克隆 anti-Lamin A/C antibody is suitable to detect Lamin A/C in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN7881457
发货至: 中国
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Quick Overview for Lamin A/C 抗体 (ABIN7881457)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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人, 小鼠, 大鼠

宿主

  • 149
  • 49
  • 2
  • 1
小鼠

克隆类型

  • 107
  • 94
单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

1073CT3-1-3
  • 原理

    Lamin A/C Antibody

    纯化方法

    Protein G purified

    免疫原

    Recombinant human LMNA was used as the immunogen for the Lamin A/C antibody.

    亚型

    IgG1, kappa
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the Lamin A/C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the LMNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Lamin A/C (LMNA)

    别名

    Lamin A/C

    背景

    Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone. [UniProt]

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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