PAK1 抗体 (AA 2-248)
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Quick Overview for PAK1 抗体 (AA 2-248) (ABIN7871790)
抗原
See all PAK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-248
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原理
- p21-activated kinase 1 Antibody / PAK1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids S2-M248) was used as the immunogen for the p21-activated kinase 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the p21-activated kinase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the p21-activated kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PAK1 (P21-Activated Kinase 1 (PAK1))
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别名
- p21-activated kinase 1
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背景
- Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activated kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternative transcripts of this gene have been found, but their full-length natures have not yet been determined. The PAK1 gene is mapped to 11q13-q14 by inclusion within a mapped clone.
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UniProt
- Q13153
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途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
抗原
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