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MMP14 抗体 (AA 145-174)

The 兔 多克隆 anti-MMP14 antibody is suitable to detect MMP14 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC (p) 和 FACS.
产品编号 ABIN7870722
发货至: 中国
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Quick Overview for MMP14 抗体 (AA 145-174) (ABIN7870722)

抗原

See all MMP14 抗体
MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

适用

  • 110
  • 57
  • 55
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 96
  • 13
  • 2
  • 1

克隆类型

  • 66
  • 46
多克隆

标记

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This MMP14 antibody is un-conjugated

应用范围

  • 78
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  • 11
  • 9
  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 10
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    • 2
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    • 2
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    • 1
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    • 1
    AA 145-174

    原理

    MMP14 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 145-174 from the human protein was used as the immunogen for the MMP14 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MMP14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

    别名

    MMP14

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.

    UniProt

    P50281

    途径

    Autophagy
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