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MMP14 抗体 (C-Term)

This 小鼠 单克隆 antibody specifically detects MMP14 in WB, IF, IHC (p) 和 IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN4911994
发货至: 中国
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北京 101111
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Quick Overview for MMP14 抗体 (C-Term) (ABIN4911994)

抗原

See all MMP14 抗体
MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

适用

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宿主

  • 119
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  • 1
小鼠

克隆类型

  • 89
  • 45
单克隆

标记

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This MMP14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

3A6
  • 抗原表位

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    AA 470-499, C-Term

    原理

    MMP14 (3A6) Monoclonal Antibody

    交叉反应

    纯化方法

    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14.

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin, Sodium azide

    注意事项

    This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

    别名

    MMP14

    背景

    Synonyms: MMP-14, MMP-X1, MT-MMP, MT1MMP, MTMMP1, WNCHRS, MT1-MMP, MT-MMP 1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14

    Background: Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

    基因ID

    4323

    UniProt

    P50281

    途径

    Autophagy
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