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MMP14 抗体 (C-Term)

MMP14 适用: 人 WB 宿主: 兔 Polyclonal RB41662 unconjugated
产品编号 ABIN1881546
发货至: 中国
  • 抗原 See all MMP14 抗体
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    抗原表位
    • 13
    • 12
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 495-523, C-Term
    适用
    • 94
    • 34
    • 33
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 83
    • 11
    • 1
    克隆类型
    • 74
    • 21
    多克隆
    标记
    • 51
    • 8
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MMP14 antibody is un-conjugated
    应用范围
    • 64
    • 47
    • 36
    • 18
    • 14
    • 11
    • 9
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M, Pig, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human MMP14.
    克隆位点
    RB41662
    亚型
    Ig Fraction
    Top Product
    Discover our top product MMP14 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Sakr, Takino, Domoto, Nakano, Wong, Sasaki, Nakanuma, Sato: "GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase." in: Cancer science, Vol. 101, Issue 11, pp. 2368-74, (2010) (PubMed).

  • 抗原
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    别名
    MMP14 (MMP14 产品)
    背景
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
    分子量
    65894
    NCBI登录号
    NP_004986
    UniProt
    P50281
    途径
    Autophagy
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