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ATG5 抗体 (AA 118-155)

This 兔 多克隆 antibody specifically detects ATG5 in IHC (p). It exhibits reactivity toward 斑马鱼.
产品编号 ABIN7870256
发货至: 中国
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Quick Overview for ATG5 抗体 (AA 118-155) (ABIN7870256)

抗原

See all ATG5 抗体
ATG5 (ATG5 Autophagy Related 5 (ATG5))

适用

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斑马鱼

宿主

  • 101
  • 54
  • 4
  • 1

克隆类型

  • 86
  • 74
多克隆

标记

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This ATG5 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 36
    • 16
    • 9
    • 5
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    AA 118-155

    原理

    Zebrafish Atg5 Antibody / Autophagy protein 5

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived zebrafish Atg5 recombinant protein (amino acids S118-L155) was used as the immunogen for the Zebrafish Atg5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Atg5 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Atg5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ATG5 (ATG5 Autophagy Related 5 (ATG5))

    别名

    Atg5

    背景

    Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is also known as APG5 or ASP, and this gene is mapped to 6q21. It is found that knockdown of ATG5 in hepatocytes increased triglyceride levels with oleate or a second endogenous stimulus for triglyceride formation. These hepatocytes with ATG5 knockdown also had increased lipid droplet number and size. ATG5 is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.

    UniProt

    F1RDC0

    途径

    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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