GRB2 抗体 (AA 1-217)
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北京 101111
Quick Overview for GRB2 抗体 (AA 1-217) (ABIN7868837)
抗原
See all GRB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-217
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原理
- Growth factor receptor bound protein 2 Antibody / GRB2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-V217) was used as the immunogen for the Growth factor receptor bound protein 2 antibody.
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亚型
- IgG
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anti-Growth Factor Receptor-Bound Protein 2 (GRB2) antibody
GRB2 适用: 人, 小鼠, 大鼠, 犬, 小鸡 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (C-Term) antibodyVerified GRB2 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) antibodyGRB2 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (C-Term) antibodyKO Validated GRB2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) antibodyKD Validated GRB2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6275 unconjugated Recombinant Antibody
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 89-118) antibodyGRB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) antibodyGRB2 适用: 人, 小鼠, 大鼠, Cow, Hamster WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 156-217) antibodyGRB2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 89-118) antibodyGRB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15648 unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 187-216) antibodyGRB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11305-11306 unconjugated
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应用备注
- Optimal dilution of the Growth factor receptor bound protein 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Growth factor receptor bound protein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
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别名
- Growth factor receptor bound protein 2
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背景
- GRB2, Growth factor receptor-bound protein 2, is an adaptor protein involved in signal transduction/cell communication. The GRB2 gene encodes a protein that has homology to noncatalytic regions of the SRC oncogene product. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. In humans, the GRB2 protein is encoded by the GRB2 gene. Grb2 is widely expressed and is essential for multiple cellular functions. The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the sem-5 gene of Caenorhabditis elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P62993
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途径
- RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
抗原
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