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SET/TAF-I 抗体

This 小鼠单克隆 antibody specifically detects SET/TAF-I in WB, IF 和 FACS. It exhibits reactivity toward 人.

产品编号 ABIN7863384

发货至: 中国

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Quick Overview for SET/TAF-I 抗体 (ABIN7863384)

抗原

See all SET/TAF-I (SET) 抗体

SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This SET/TAF-I antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-SET-1C6

Discover our top product SET Primary Antibody

原理

SET Antibody

特异性

Protein phosphatase 2A (PP2A) is a major mammalian protein serine/threonine phosphatase that regulates diverse cellular processes. Inhibitor 1 of PP2A (I1PP2A) and inhibitor 2 of PP2A (I2PP2A), which share large sequence similarity, are heat-stable protein inhibitors of the cellular phosphatase activity of PP2A. I1PP2A and I2PP2A were initially characterized as putative HLA class II associated proteins Phap I and Phap II. These inhibitor proteins act noncompetitively to selectively inhibit PP2A, but do not affect the phosphatase activity of the related proteins PP1, PP2B and PP2C. The I1PP2A protein is localized to both the cytoplasm and the nucleus. In contrast, I2PP2A is located predominantly in the nucleus and is highly expressed in Wilms tumor cells. Transient expression of I2PP2A in HEK-293 cells leads to an increase in the DNA binding activity of the proto-oncogene c-Jun.

纯化方法

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

免疫原

Recombinant full-length human SET protein

亚型

IgG1
anti-SET Nuclear Oncogene (SET) (N-Term) antibody
Verified SET 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-SET Nuclear Oncogene (SET) antibody
SET 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SET Nuclear Oncogene (SET) antibody
SET 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-SET Nuclear Oncogene (SET) (AA 125-175) antibody
SET 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated

anti-SET Nuclear Oncogene (SET) (AA 1-277) antibody
SET 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal M1-F5 unconjugated

anti-SET Nuclear Oncogene (SET) antibody
SET 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB1530 unconjugated Recombinant Antibody

anti-SET Nuclear Oncogene (SET) (N-Term) antibody
SET 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-SET Nuclear Oncogene (SET) (AA 125-175) antibody
SET 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated

anti-SET Nuclear Oncogene (SET) antibody
SET 适用: 人, 小鼠, 大鼠 WB, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-SET Nuclear Oncogene (SET) (N-Term) antibody
SET 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

别名

SET

背景

2PP2A, HLA DR associated protein II, IGAAD, Inhibitor of granzyme A activated DNase, inhibitor-2 of protein phosphatase-2A, IPP2A2, PHAPII, Phosphatase 2A inhibitor I2PP2A, protein phosphatase type 2A inhibitor, TAFI, Template-Activating Factor-I, chromatin remodelling factor, SET nuclear oncogene, SET translocation (myeloid leukemia-associated)
HeLa or HepG2 cells.

分子量

39kDa

基因ID

6418, 436687

UniProt

Q01105

途径

Apoptosis