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IL-6 抗体 (AA 1-200)

The 小鼠 单克隆 anti-IL-6 antibody (Clone IL6-4642) (ABIN7858570) specifically detects IL-6 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7858570
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-6 抗体 (AA 1-200) (ABIN7858570)

抗原

See all IL-6 (IL6) 抗体
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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小鼠

克隆类型

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单克隆

标记

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This IL-6 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

IL6-4642
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    AA 1-200

    原理

    IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody

    特异性

    IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. It plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6.It is involved in host defense, acute phase reactions, immune responses, and hematopoiesis.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-200) of human IL-6 protein (exact sequence is proprietary)

    亚型

    IgG2, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    IL-6

    背景

    B-cell stimulatory factor 2 (BSF-2), CTL differentiation factor (CDF), Cytotoxic T cell differentiation factor, Hepatocyte stimulating factor (HSF), HPGF, Hybridoma growth factor Interferon beta-2, Hybridoma plasmacytoma growth factor, IFN-beta-2 (IFNB2)

    Human heart or adrenal gland. Stimulated peritoneal macrophages.

    分子量

    21kDa

    基因ID

    3569, 654458

    UniProt

    P05231

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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