Retinoblastoma 1 抗体 (AA 40-921)
Our Local Distributor
北京 101111
Quick Overview for Retinoblastoma 1 抗体 (AA 40-921) (ABIN7825771)
抗原
See all Retinoblastoma 1 (RB1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 40-921
-
原理
- Anti-RB1 Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-RB1 Antibody catalog # A00039-3. Tested in WB, IHC, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human RB1 recombinant protein (Position: E40-D921). Human RB1 shares 91.6% and 90.7% amino acid (aa) sequence identity with mouse and rat RB1, respectively.
-
亚型
- IgG
-
-
anti-Retinoblastoma 1 (RB1) (pSer780) antibody
RB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer780) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer807) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer795) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer807), (pSer811) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (AA 639-778) antibodyRB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Retinoblastoma 1 (RB1)
-
别名
- RB1
-
背景
- The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
-
分子量
- 110 kDa
-
基因ID
- 5925
-
UniProt
- P06400
-
途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
抗原
-
