ATG5 抗体 (AA 118-155)
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北京 101111
Quick Overview for ATG5 抗体 (AA 118-155) (ABIN7825269)
抗原
See all ATG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 118-155
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原理
- Anti-Zebrafish ATG5 Antibody
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产品特性
- Anti-Zebrafish ATG5 Antibody catalog # AZF1RDC0. Tested in IHC applications. This antibody reacts with Zebrafish.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived zebrafish ATG5 recombinant protein (Position: S118-L155).
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亚型
- IgG
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应用备注
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Immunohistochemistry, 2-5 μg/mL, Zebrafish
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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别名
- ATG5
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背景
- Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is also known as APG5 or ASP, and this gene is mapped to 6q21. It is found that knockdown of ATG5 in hepatocytes increased triglyceride levels with oleate or a second endogenous stimulus for triglyceride formation. These hepatocytes with ATG5 knockdown also had increased lipid droplet number and size. ATG5 is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
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基因ID
- 494180
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途径
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
抗原
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