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ATG5 抗体 (C-Term)

ATG5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260107
发货至: 中国
  • 抗原 See all ATG5 抗体
    ATG5 (ATG5 Autophagy Related 5 (ATG5))
    抗原表位
    • 16
    • 13
    • 7
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    • 5
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    C-Term
    适用
    • 102
    • 43
    • 35
    • 7
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    • 5
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    • 4
    • 4
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    人, 小鼠, 大鼠
    宿主
    • 77
    • 22
    • 4
    • 1
    克隆类型
    • 76
    • 28
    多克隆
    标记
    • 57
    • 8
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    • 6
    • 1
    • 1
    • 1
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    • 1
    • 1
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    This ATG5 antibody is un-conjugated
    应用范围
    • 79
    • 53
    • 35
    • 19
    • 18
    • 17
    • 14
    • 13
    • 10
    • 10
    • 6
    • 3
    • 3
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    APG5L/ATG5 Antibody detects endogenous levels of total APG5L/ATG5.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human APG5L/ATG5, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ATG5 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Li, Li, Zeng, Yang, Liu, Zhang, Song, Yao, Ma, Li, Wang, Wei: "Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis." in: Journal of virology, Vol. 92, Issue 8, (2018) (PubMed).

  • 抗原
    ATG5 (ATG5 Autophagy Related 5 (ATG5))
    别名
    ATG5 (ATG5 产品)
    别名
    APG5 antibody, APG5-LIKE antibody, APG5L antibody, ASP antibody, hAPG5 antibody, ATG5 antibody, CG1643 antibody, DmAtg5 antibody, Dmel\\CG1643 antibody, atg5 antibody, 2010107M05Rik antibody, 3110067M24Rik antibody, AW319544 antibody, Apg5l antibody, Atg5l antibody, C88337 antibody, Paddy antibody, apg5l antibody, zgc:100934 antibody, ATATG5 antibody, AUTOPHAGY 5 antibody, MKP11.20 antibody, MKP11_20 antibody, autophagy related 5 antibody, Autophagy-related 5 antibody, ATG5 autophagy related 5 homolog (S. cerevisiae) antibody, autophagy related 5 L homeolog antibody, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 antibody, autophagy protein Apg5 family antibody, ATG5 antibody, Atg5 antibody, atg5 antibody, atg5.L antibody, APG5 antibody
    背景

    Description: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.

    Gene: ATG5

    分子量
    32kDa
    基因ID
    9474
    UniProt
    Q9H1Y0
    途径
    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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