CYP7A1 抗体 (AA 351-400)
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- 抗原 See all CYP7A1 抗体
- CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
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抗原表位
- AA 351-400
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP7A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 (详细)
- Rat
- 预测反应
- Pig,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CYP7A1
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Nrf2 is crucial for the down-regulation of Cyp7a1 induced by arachidonic acid in Hepg2 cells." in: Environmental toxicology and pharmacology, Vol. 52, pp. 21-26, (2017) (PubMed).
: "Pyrazinamide Induced Rat Cholestatic Liver Injury through Inhibition of FXR Regulatory Effect on Bile Acid Synthesis and Transport." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 152, Issue 2, pp. 417-28, (2016) (PubMed).
: "Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters." in: Life sciences, Vol. 151, pp. 50-60, (2016) (PubMed).
: "Preferential gene expression and epigenetic memory of induced pluripotent stem cells derived from mouse pancreas." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 5, pp. 367-81, (2015) (PubMed).
: "Chronic unpredictable mild stress combined with a high-fat diets aggravates atherosclerosis in rats." in: Lipids in health and disease, Vol. 13, pp. 77, (2014) (PubMed).
: "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 11, pp. 1373-81, (2014) (PubMed).
: "Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 44, Issue 12, pp. 1018-26, (2012) (PubMed).
: "
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Nrf2 is crucial for the down-regulation of Cyp7a1 induced by arachidonic acid in Hepg2 cells." in: Environmental toxicology and pharmacology, Vol. 52, pp. 21-26, (2017) (PubMed).
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- 抗原
- CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
- 别名
- CYP7A1 (CYP7A1 产品)
- 别名
- CP7A antibody, CYP7 antibody, CYPVII antibody, CHAP antibody, CYP7S1 antibody, cyp7a1a antibody, zgc:63920 antibody, cytochrome P450 family 7 subfamily A member 1 antibody, cytochrome P450, family 7, subfamily a, polypeptide 1 antibody, cytochrome P450, family 7, subfamily A, polypeptide 1 antibody, cholesterol 7-alpha-hydroxylase antibody, CYP7A1 antibody, Cyp7a1 antibody, cyp7a1 antibody
- 背景
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Synonyms: CP7A, CYP7, CYPVII, Cholesterol 7-alpha-monooxygenase, Cholesterol 7-alpha-hydroxylase, Cytochrome P45 7A1, CYP7A1
Background: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
- 基因ID
- 1581
- UniProt
- P22680
- 途径
- Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha
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