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Histone 3 抗体 (AA 71-136)

Name: Histone 3 抗体 (AA 71-136)
SKU: ABIN739109
Availability: OutOfStock

This anti-Histone 3 antibody is a 兔多克隆 antibody detecting Histone 3 in WB, ELISA, ICC, IHC (p), FACS, IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 13+ publications.

K562 Cell lysates probed with Histone H3 Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 60 minutes at 37°C. (Histone 3 抗体 (AA 71-136))

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Histone H3 Polyclonal Antibody, Unconjugated (ABIN739109) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Histone 3 抗体 (AA 71-136))

IHC

Mouse splenocytes probed with Rabbit Anti-Histone H3 Polyclonal Antibody, Unconjugated . (Histone 3 抗体 (AA 71-136))

FACS

Paraformaldehyde-fixed, paraffin embedded human colon cancer, Antigen retrieval by boiling in sodium citrate buffer (pH6. (Histone 3 抗体 (AA 71-136))

IHC (p)

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-Histone H3 Polyclonal Antibody, Unconjugated (ABIN739109) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. (Histone 3 抗体 (AA 71-136))

Formalin-fixed and paraffin embedded mouse intestine labeled with Rabbit Anti Histone H3 Polyclonal Antibody, Unconjugated (ABIN739109) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Histone 3 抗体 (AA 71-136))

IHC

6 images

(13 references)

产品编号 ABIN739109

发货至: 中国

Datasheet as PDF

Quick Overview for Histone 3 抗体 (AA 71-136) (ABIN739109)

抗原

See all Histone 3 (H3) 抗体

Histone 3 (H3) (Histone H3 (H3))

适用

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人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Histone 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product H3 Primary Antibody

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AA 71-136

交叉反应

人, 小鼠, 大鼠

预测反应

Cow,Pig,Rabbit,Drosophila

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Histone H3

亚型

IgG
anti-Histone H3 (H3) (H3K4me) antibody
H3 适用: 人 WB, IF, ChIP, IP, ChIP-seq, CUT&RUN 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K27ac) antibody
H3 适用: 人, Saccharomyces cerevisiae WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (3meLys4) antibody
H3 适用: 人, Saccharomyces cerevisiae WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K9ac) antibody
H3 适用: 人, 小鼠 WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K36me3) antibody
H3 适用: 人, 小鼠 WB, ChIP, DB, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 小鼠 Monoclonal MABI 0333 unconjugated

anti-Histone H3 (H3) (H3K4me3) antibody
H3 适用: 人, 小鼠, Saccharomyces cerevisiae WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (C-Term) antibody
H3 适用: 人 WB, IHC, ChIP, IP 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K9me2) antibody
H3 适用: 人 WB, IF, IHC, ChIP, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3R2me2) antibody
H3 适用: 人 WB, IF, ChIP, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K4me3) antibody
H3 适用: 人 WB, IF, IHC, ChIP, IP, DB, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Si, Meng, Gao, Hui, Li, Liu, Yang: "Linagliptin protects rat carotid artery from balloon injury and activates the NRF2 antioxidant pathway." in: Experimental animals, Vol. 68, Issue 1, pp. 81-90, (2019) (PubMed).

Zhang, Zhang, Li, Wang, Gu, Feng, Wei, Peng, Zhang, Su, Wang, Li, Yang, Wong, Yang, Ma: "Uncoupling Protein 2 Inhibits Myointimal Hyperplasia in Preclinical Animal Models of Vascular Injury." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Joy, Gau, Castellucci, Prywes, Roy: "The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms." in: The Journal of biological chemistry, Vol. 292, Issue 28, pp. 11777-11791, (2017) (PubMed).

Yang, Liu, Jiang, Wang, Zhang: "Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model." in: Frontiers in pharmacology, Vol. 8, pp. 44, (2017) (PubMed).

Shen, Wu, Liu, Zhao, Zhao: "Epigallocatechin-3-gallate alleviates paraquat-induced acute lung injury and inhibits upregulation of toll-like receptors." in: Life sciences, Vol. 170, pp. 25-32, (2016) (PubMed).

Qian, Zhang, Hu, Xu, Chen, Hu, Zhao, Liu: "Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status." in: Biomaterials, Vol. 70, pp. 12-22, (2015) (PubMed).

Duan, Liu, Liang, Yang, Xia, Wang, Chen, Yu: "Oestrogen receptor-mediated expression of Olfactomedin 4 regulates the progression of endometrial adenocarcinoma." in: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 863-74, (2014) (PubMed).

Tang, Chen, Liang, Rong, Yao, Yang, Wu: "Selective antegrade cerebral perfusion attenuating the TLR4/NF-?B pathway during deep hypothermia circulatory arrest in a pig model." in: Cardiology, Vol. 128, Issue 3, pp. 243-50, (2014) (PubMed).

Wang, Ma, Su: "NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells." in: Biological trace element research, Vol. 153, Issue 1-3, pp. 403-10, (2013) (PubMed).

Liu, Ji, Zhang, Tong, Pan, Liu, Zhang, Huang, Su, Willard, Zheng: "Nonenzymatic glycation of high-density lipoprotein impairs its anti-inflammatory effects in innate immunity." in: Diabetes/metabolism research and reviews, Vol. 28, Issue 2, pp. 186-95, (2012) (PubMed).

Zhou, Zhou, Wang, Mu, Wu, Guo, Zhang, Wu: "Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro." in: Acta pharmacologica Sinica, Vol. 33, Issue 1, pp. 120-6, (2012) (PubMed).
抗原

Histone 3 (H3) (Histone H3 (H3))

别名

Histone H3

背景

Synonyms: Histone H3, H3.1, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FA, H3FL, H3FC, H3FB, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ, H3.2, HIST2H3A, HIST2H3C, HIST2H3D, H3F2, H3FM, H3.3, H3F3A, H3F3B, H3.3A, H3.3B, H3F3, PP781, H3.3C, H3F3C, H3.5, H3.1t, HIST3H3, H3FT
Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

基因ID

3020

UniProt

P84243