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DNAJC3 抗体 (AA 351-450) (Biotin)

DNAJC3 适用: 小鼠, 大鼠 ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN735550
发货至: 中国
  • 抗原 See all DNAJC3 抗体
    DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
    抗原表位
    • 14
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    适用
    • 25
    • 18
    • 16
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 37
    • 3
    克隆类型
    • 38
    • 2
    多克隆
    标记
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNAJC3 antibody is conjugated to Biotin
    应用范围
    • 14
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human p58ipk/DNAJC3
    亚型
    IgG
    Top Product
    Discover our top product DNAJC3 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
    别名
    DNAJC3 (DNAJC3 产品)
    别名
    ERdj6 antibody, HP58 antibody, P58 antibody, P58IPK antibody, PRKRI antibody, zgc:56356 antibody, zgc:77731 antibody, wu:fb64f06 antibody, DNAJC3 antibody, dnajc3 antibody, DDBDRAFT_0186884 antibody, DDBDRAFT_0233602 antibody, DDB_0186884 antibody, DDB_0233602 antibody, cg8286 antibody, AA408985 antibody, AU067833 antibody, Dnajc3a antibody, Dnajc3b antibody, Prkri antibody, mp58 antibody, p58 antibody, p58IPK antibody, fc17a06 antibody, prkri antibody, wu:fc17a06 antibody, DnaJ heat shock protein family (Hsp40) member C3 antibody, DnaJ (Hsp40) homolog, subfamily C, member 3a antibody, DNAJ heat shock N-terminal domain-containing protein antibody, DnaJ heat shock protein family (Hsp40) member C3 L homeolog antibody, DnaJ (Hsp40) homolog, subfamily C, member 3b antibody, DNAJC3 antibody, dnajc3a antibody, dnajc3 antibody, dnajc3.L antibody, Dnajc3 antibody, dnajc3b antibody
    背景

    Synonyms: DNAJC3, Protein Kinase Inhibitor P58, DnaJ homolog subfamily C member 3, HP58, Interferon induced, double stranded RNA activated protein kinase inhibitor, P58, p58 ipk , P58IPK, PRKRI, Protein kinase inhibitor of 58 kDa, Protein kinase inhibitor p58.

    Background: DNAJC3 may act as an inhibitor of both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2/PKR to catalyze phosphorylation of the EIF2A. It also functions as a Co-chaperone of HSPA8/HSC70 and is involved in the unfolded protein response (UPR) during ER stress. It has been reported that this protein stimulates the ATPase activity of HSPA8/HSC70.DNAJC3 is also involved in ativiral defense - it is activated in response to infection by influenza virus through the dissociation of DNAJB1. DNAJC3 is widely expressed and can be found at high levels in the testis and pancreas (expression in cell lines is variable).

    基因ID
    5611
    UniProt
    Q13217
    途径
    ER-Nucleus Signaling
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