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- 抗原 See all DNAJC3 抗体
- DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DNAJC3 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- DNAJC3 Antibody detects endogenous levels of total DNAJC3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human DNAJC3, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product DNAJC3 Primary Antibody
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anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 1-234) antibody
DNAJC3 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4D3-F2 unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 1-226) antibodyDNAJC3 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 277-496) antibodyDNAJC3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 270-462) antibodyDNAJC3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 189-223) antibodyDNAJC3 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB57780 unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) (AA 1-234) antibodyDNAJC3 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
- 别名
- DNAJC3 (DNAJC3 产品)
- 别名
- ERdj6 antibody, HP58 antibody, P58 antibody, P58IPK antibody, PRKRI antibody, zgc:56356 antibody, zgc:77731 antibody, wu:fb64f06 antibody, DNAJC3 antibody, dnajc3 antibody, DDBDRAFT_0186884 antibody, DDBDRAFT_0233602 antibody, DDB_0186884 antibody, DDB_0233602 antibody, cg8286 antibody, AA408985 antibody, AU067833 antibody, Dnajc3a antibody, Dnajc3b antibody, Prkri antibody, mp58 antibody, p58 antibody, p58IPK antibody, fc17a06 antibody, prkri antibody, wu:fc17a06 antibody, DnaJ heat shock protein family (Hsp40) member C3 antibody, DnaJ (Hsp40) homolog, subfamily C, member 3a antibody, DNAJ heat shock N-terminal domain-containing protein antibody, DnaJ heat shock protein family (Hsp40) member C3 L homeolog antibody, DnaJ (Hsp40) homolog, subfamily C, member 3b antibody, DNAJC3 antibody, dnajc3a antibody, dnajc3 antibody, dnajc3.L antibody, Dnajc3 antibody, dnajc3b antibody
- 背景
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Description: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Gene: DNAJC3
- 分子量
- 54 kDa
- 基因ID
- 5611
- UniProt
- Q13217
- 途径
- ER-Nucleus Signaling
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