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IL-6 抗体

This anti-IL-6 antibody is a 小鼠 单克隆 antibody detecting IL-6 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7673405
发货至: 中国

Quick Overview for IL-6 抗体 (ABIN7673405)

抗原

See all IL-6 (IL6) 抗体
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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小鼠

克隆类型

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单克隆

标记

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This IL-6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

9G1
  • 原理

    IL6 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    interleukin 6(interferon, beta 2)

    亚型

    IgG2b
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    IL6

    背景

    Synonyms: Interleukin-6 (IL-6)|B-cell stimulatory factor 2 (BSF-2)|CTL differentiation factor (CDF)|Hybridoma growth factor|Interferon beta-2 (IFN-beta-2)|IL6|IFNB2

    Background: Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

    分子量

    24 kDa

    基因ID

    3569

    UniProt

    P05231

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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