Insulin 抗体
Quick Overview for Insulin 抗体 (ABIN7670774)
抗原
See all Insulin (INS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Insulin Monoclonal Antibody(Detector)
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纯化方法
- Protein A/G Purification
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免疫原
- Human INS Native Protein
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亚型
- IgG1
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应用备注
- ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- Insulin (INS)
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别名
- Insulin
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背景
- IDDM2,ILPR,IRDN,MODY10,Insulin is a peptide hormone,produced by beta cells of the pancreas,and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization,protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule,proinsulin,which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin,while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.
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UniProt
- P01308
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途径
- NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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