Caspase 9 抗体
Quick Overview for Caspase 9 抗体 (ABIN7670508)
抗原
See all Caspase 9 (CASP9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Caspase-9 Monoclonal Antibody
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纯化方法
- Protein A/G Purification
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免疫原
- Recombinant Human Caspase-9 protein expressed by E.coli
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亚型
- IgG2a
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应用备注
- WB 1:250-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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别名
- Caspase-9
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背景
- Apoptosis related cysteine peptidase,Apoptotic protease-activating factor 3,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-like apoptotic protease 6,protein phosphatase 1,regulatory subunit 56,RNCASP9,MCH,Apoptotic protease Mch,PPP1R,ICE-LAP,CASP9,APAF-3,APAF3,ICE-LAP6,MCH6,PPP1R56,caspase-9,Caspase 9,CASP-9,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3 (APAF-3),ICE-like apoptotic protease 6 (ICE-LAP6),Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
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分子量
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Calculated MW: 46 kDa
ObservedMW: 35 kDa,47 kDa
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UniProt
- P55211
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途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
抗原
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