MHC Class II HLA-DP/DQ/DR 抗体 (CF®568)
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北京 101111
Quick Overview for MHC Class II HLA-DP/DQ/DR 抗体 (CF®568) (ABIN7657067)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HLA-DP/-DQ/-DR (MHC II)(CR3/43), CF568 conjugate
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产品特性
- Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Cells from human tonsil
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亚型
- IgG1, kappa
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anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibody
HLA-DP/DQ/DR 适用: 人 FACS, IF, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal rHLA-Pan-3475 unconjugated Recombinant Antibody
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IF, WB, IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal HLA-Pan-2967R unconjugated Recombinant Antibody
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IF, WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CR3-43 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyGMP Grade HLA-DP/DQ/DR 适用: 人 FACS 宿主: 小鼠 Monoclonal IVA12 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibody (PE)HLA-DP/DQ/DR 适用: 人 FACS 宿主: 小鼠 Monoclonal WR18 PE
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal WR18 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibody (FITC)GMP Grade HLA-DP/DQ/DR 适用: 人 FACS 宿主: 小鼠 Monoclonal IVA12 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Ramos, Raji cells. Tonsil, Spleen or lymph node.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
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别名
- HLA-DP/-DQ/-DR
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背景
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Synonyms: HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5,
Gene Symbol: HLA-DP, HLA-DQ, HLA-DR
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分子量
- 36 kDa (? chain) and 27 kDa (? chain)
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基因ID
- 3115, 3117, 3122
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UniProt
- P04440, P01908, P01909, P01920, P01903
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途径
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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