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MHC Class II HLA-DP/DQ/DR 抗体 (FITC)

GMP Grade HLA-DP/DQ/DR 适用: 人 宿主: 小鼠 Monoclonal IVA12 FITC
产品编号 ABIN7077534
发货至: 中国
  • 抗原 See all MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) products
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    适用
    • 17
    • 1
    宿主
    • 15
    • 2
    小鼠
    克隆类型
    • 17
    单克隆
    标记
    • 11
    • 3
    • 2
    • 1
    This MHC Class II HLA-DP/DQ/DR antibody is conjugated to FITC
    应用范围
    请咨询
    产品特性
    The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.
    纯化方法
    Purified
    纯度
    >95 %
    质量等级
    GMP Grade
    免疫原
    Priess human B cell line
    克隆位点
    IVA12
    亚型
    IgG1 kappa
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    别名
    HLA-DR, DP, DQ (HLA-DP/DQ/DR 产品)
    背景
    The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.
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