MHC Class II HLA-DP/DQ/DR 抗体
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- 抗原 See all MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) products
- MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MHC Class II HLA-DP/DQ/DR antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 产品特性
- The clone IVA12 recognizes the shared epitopes of human leucocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS expressed HLA-DR only.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 免疫原
- Priess human B cell line
- 克隆位点
- IVA12
- 亚型
- IgG1 kappa
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anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibody
HLA-DP/DQ/DR 适用: 人 FACS, IF, IHC, Coat, ELISA, StM 宿主: 小鼠 Monoclonal rHLA-Pan-3475 unconjugated Recombinant Antibody
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IF, WB, IHC, Coat, ELISA, StM 宿主: 兔 Monoclonal HLA-Pan-2967R unconjugated Recombinant Antibody
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IF, WB, IHC, Coat, ELISA, StM 宿主: 小鼠 Monoclonal CR3-43 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal WR18 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibody (FITC)GMP Grade HLA-DP/DQ/DR 适用: 人 宿主: 小鼠 Monoclonal IVA12 FITC
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- 应用备注
- Each lot of this antibody has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg is sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
- 别名
- HLA-DR, DP, DQ (HLA-DP/DQ/DR 产品)
- 背景
- The clone IVA12 recognizes the shared epitopes of human leucocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS expressed HLA-DR only.
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