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CSNK2A1/CK II alpha 抗体 (AA 201-300)

Name: CSNK2A1/CK II alpha 抗体 (AA 201-300)
SKU: ABIN731978
Availability: OutOfStock

CSNK2A1 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Human HepG2 cells probed with CK II alpha Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C. (CSNK2A1/CK II alpha 抗体 (AA 201-300))

Lane 1: rat brain lysates Lane 2: rat heart lysates probed with Anti CK II alpha/STKPolyclonal Antibody, Unconjugated (ABIN731978) at 1:200 in 4 °C. (CSNK2A1/CK II alpha 抗体 (AA 201-300))

SDS

2 images

产品编号 ABIN731978

发货至: 中国

Datasheet as PDF

抗原 See all CSNK2A1/CK II alpha (CSNK2A1) 抗体

CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))
抗原表位
11

11

7

6

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 201-300
适用
81

57

52

7

6

6

4

4

4

4

3

3

3

2

2

2

1

1

1

1
人, 大鼠
宿主
75

6
兔
Compatible Secondaries
克隆类型
73

8
多克隆
标记
51

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1
This CSNK2A1/CK II alpha antibody is un-conjugated
应用范围
68

32

24

9

9

9

4

2

2

1
Western Blotting (WB), ELISA

交叉反应

人, 大鼠

预测反应

Mouse,Dog,Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CK II alpha

亚型

IgG

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应用备注

WB 1:300-5000
ELISA 1:500-1000

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

别名

CK 2 alpha (CSNK2A1 产品)

别名

CK2A2 antibody, CSNK2A1 antibody, CK2A1 antibody, CKII antibody, CSNK2A3 antibody, CK2A antibody, Ck2a antibody, BmCK2a antibody, wu:fi38e04 antibody, wu:fi38h03 antibody, csnk2a1 antibody, CK-II antibody, CK2 antibody, Ckiialpha antibody, Csnk2a1-rs4 antibody, ck2a1 antibody, casein kinase 2 alpha 2 antibody, casein kinase 2 alpha 1 antibody, casein kinase 2 alpha subunit antibody, casein kinase 2, alpha 1 polypeptide antibody, CK2 protein kinase alpha 2 antibody, casein kinase II alpha subunit antibody, Casein kinase II alpha subunit antibody, casein kinase 2, alpha 1 polypeptide S homeolog antibody, CSNK2A2 antibody, CSNK2A1 antibody, ck2a antibody, Ck2a antibody, csnk2a1 antibody, cka2 antibody, Ckiialpha antibody, CK2A1 antibody, Csnk2a1 antibody, csnk2a1.S antibody

背景

Synonyms: CKII, CK2A1, CSNK2A3, Casein kinase II subunit alpha, CK II alpha, CSNK2A1
Background: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV. Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation.

基因ID

1457

UniProt

P68400

途径

SARS-CoV-2 Protein Interactome