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ATG5 抗体 (AA 1-119) (CF®405S)

This anti-ATG5 antibody is a 小鼠 单克隆 antibody detecting ATG5 in WB, IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7649687
发货至: 中国

Quick Overview for ATG5 抗体 (AA 1-119) (CF®405S) (ABIN7649687)

抗原

See all ATG5 抗体
ATG5 (ATG5 Autophagy Related 5 (ATG5))

适用

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宿主

  • 80
  • 43
  • 4
  • 1
小鼠

克隆类型

  • 78
  • 50
单克隆

标记

  • 65
  • 7
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  • 2
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This ATG5 antibody is conjugated to CF®405S

应用范围

  • 87
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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

ATG5-2492
  • 抗原表位

    • 25
    • 16
    • 9
    • 5
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    • 3
    • 3
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-119

    原理

    ATG5 (Autophagy Marker)(ATG5/2492), CF405S conjugate

    产品特性

    Autophagy protein 5 (ATG5), in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. ATG5 is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy, a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment of human ATG5 protein (around aa 1-119)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: THP1, PANC-1, Raji or HeLa cells. Brain, Ovary, Endometrium, Colon or Duodenum (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    ATG5 (ATG5 Autophagy Related 5 (ATG5))

    别名

    ATG5

    背景

    Synonyms: Autophagy protein 5, ATG5, Autophagy related 5, APG5-like, Apoptosis-specific protein

    Gene Symbol: ATG5

    分子量

    50-32 kDa

    基因ID

    9474

    UniProt

    Q9H1Y0

    途径

    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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