电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

c-MET 抗体

This anti-c-MET antibody is a Human Chimeric antibody detecting c-MET in FACS. Suitable for 人.
产品编号 ABIN7608007
发货至: 中国

Quick Overview for c-MET 抗体 (ABIN7608007)

抗原

See all c-MET (MET) 抗体
c-MET (MET) (Met Proto-Oncogene (MET))

适用

  • 223
  • 130
  • 96
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 193
  • 38
  • 3
  • 3
  • 2
Human, 兔

克隆类型

  • 184
  • 53
  • 1
Chimeric

标记

  • 125
  • 19
  • 10
  • 10
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This c-MET antibody is un-conjugated

应用范围

  • 153
  • 96
  • 42
  • 32
  • 31
  • 20
  • 15
  • 14
  • 14
  • 9
  • 8
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

8C4
  • 原理

    Anti-MET antibody(8C4), IgG1 Chimeric mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1/100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    c-MET (MET) (Met Proto-Oncogene (MET))

    别名

    MET

    背景

    This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]

    UniProt

    P08581

    途径

    RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
You are here:
Chat with us!