AGR2 抗体
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北京 101111
Quick Overview for AGR2 抗体 (ABIN7607946)
抗原
See all AGR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-AGR2 antibody(2F4), Rabbit mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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应用备注
- ELISA 1/5000-10000
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
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别名
- AGR2
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背景
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
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UniProt
- O95994
抗原
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