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Lamin A/C 抗体

This anti-Lamin A/C antibody is a 兔 单克隆 antibody detecting Lamin A/C in WB, IHC, IF, ICC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7605401
发货至: 中国

Quick Overview for Lamin A/C 抗体 (ABIN7605401)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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人, 小鼠, 大鼠

宿主

  • 111
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克隆类型

  • 110
  • 52
单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

22L53
  • 原理

    Anti-Lamin A/C Rabbit Monoclonal Antibody

    产品特性

    Anti-Lamin A/C Rabbit Monoclonal Antibody (ABIN7605401). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Lamin A/C

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000
    IHC 1:50-1:200
    ICC/IF 1:50-1:200
    FC 1:50

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    浓度

    Lot specific

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • 抗原

    Lamin A/C (LMNA)

    别名

    LMNA

    背景

    Synonyms: Prelamin-A/C,Lamin-A/C,70 kDa lamin,Renal carcinoma antigen NY-REN-32,LMNA,LMN1,

    Tissue Specificity: In the arteries, prelamin-A/C accumulation is not observed in young healthy vessels but is prevalent in medial vascular smooth muscle cells (VSMCs) from aged individuals and in atherosclerotic lesions, where it often colocalizes with senescent and degenerate VSMCs. Prelamin-A/C expression increases with age and disease. In normal aging, the accumulation of prelamin-A/C is caused in part by the down-regulation of ZMPSTE24/FACE1 in response to oxidative stress. .

    分子量

    70-74 kDa

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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