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FAS 抗体 (AA 46-279)

The 兔 多克隆 anti-FAS antibody is suitable to detect FAS in samples from 大鼠 和 小鼠. It has been validated for WB, FACS 和 ELISA.
产品编号 ABIN7601797
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FAS 抗体 (AA 46-279) (ABIN7601797)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

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大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FAS antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA
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    AA 46-279

    原理

    Anti-Fas Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Fas Antibody (ABIN7601797). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Fas recombinant protein (Position: E46-K279).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    Fas

    背景

    Synonyms: Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD_antigen: CD95, Fas, Apt1, Tnfrsf6

    Tissue Specificity: Detected in various tissues including thymus, liver, lung, heart, and adult ovary.

    Background: FAS (also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. FAS antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor (TNF) receptors and the low-affinity nerve growth factor receptor (NGFR) and it is mapped to 10q24.1. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.

    分子量

    37 kDa

    基因ID

    355

    UniProt

    P25446

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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