Retinoblastoma Binding Protein 8 抗体 (AA 307-702)
Quick Overview for Retinoblastoma Binding Protein 8 抗体 (AA 307-702) (ABIN7601241)
抗原
See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 307-702
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原理
- Anti-RBBP8 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-RBBP8 Antibody Picoband® (ABIN7601241). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RBBP8 recombinant protein (Position: R307-K702). Human RBBP8 shares 68.9% and 66.7% amino acid (aa) sequence identity with mouse and rat RBBP8, respectively.
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亚型
- IgG
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anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 452-747) antibody
RBBP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 126-331) antibodyRBBP8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) antibodyRBBP8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 1-300) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (Center) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (C-Term) antibodyRBBP8 适用: 人, Pig, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) antibodyRBBP8 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro), EIA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 791-840) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 686-735) antibodyRBBP8 适用: 人, 猴, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 8 (RBBP8) (pThr847) antibodyRBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry, 2-5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Borglum, A. D., Balslev, T., Haagerup, A., Birkebaek, N., Binderup, H., Kruse, T. A., Hertz, J. M. A new locus for Seckel syndrome on chromosome 18p11.31-q11.2. Europ. J. Hum. Genet. 9: 753-757, 2001. 2. Fusco, C., Reymond, A., Zervos, A. S. Molecular cloning and characterization of a novel retinoblastoma-binding protein. Genomics 51: 351-358, 1998. 3. Hassan, M. J., Chishti, M. S., Jamal, S. M., Tariq, M., Ahmad, W. A syndromic form of autosomal recessive congenital microcephaly (Jawad syndrome) maps to chromosome 18p11.22-q11.2. Hum. Genet. 123: 77-82, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Retinoblastoma Binding Protein 8 (RBBP8)
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别名
- RBBP8
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Retinoblastoma-binding protein 8 is a protein that in humans is encoded by the RBBP8 gene. The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind ly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
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分子量
- 130 kDa
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基因ID
- 5932
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UniProt
- Q99708
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途径
- Cell Division Cycle, DNA Damage Repair
抗原
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