TRIM29 抗体 (AA 169-549)
Quick Overview for TRIM29 抗体 (AA 169-549) (ABIN7600245)
抗原
See all TRIM29 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 169-549
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原理
- Anti-TRIM29 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-TRIM29 Antibody Picoband® (ABIN7600245). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TRIM29 recombinant protein (Position: E169-R549).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Brzoska, P. M., Chen, H., Zhu, Y., Levin, N. A., Disatnik, M.-H., Mochly-Rosen, D., Murnane, J. P., Christman, M. F. The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor. Proc. Nat. Acad. Sci. 92: 7824-7828, 1995. 2. Dou, Y., Xing, J., Kong, G., Wang, G., Lou, X., Xiao, X., Vivier, E., Li, X. C., Zhang, Z. Identification of the E3 ligase TRIM29 as a critical checkpoint regulator of NK cell functions. J. Immun. 203: 873-880, 2019. 3. Hosoi, Y., Kapp, L. N., Murnane, J. P., Matsumoto, Y., Enomoto, A., Ono, T., Miyagawa, K. Suppression of anchorage-independent growth by expression of the ataxia-telangiectasia group D complementing gene, ATDC. Biochem. Biophys. Res. Commun. 348: 728-734, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
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别名
- TRIM29
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背景
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Synonyms: Integrin alpha-L,CD11 antigen-like family member A,Leukocyte adhesion glycoprotein LFA-1 alpha chain,LFA-1A,Leukocyte function-associated molecule 1 alpha chain,CD11a,ITGAL,CD11A,
Tissue Specificity: Leukocytes.
Background: Tripartite motif-containing protein 29 is a protein that in humans is encoded by the TRIM29 gene. The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype
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分子量
- 70 kDa
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基因ID
- 23650
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UniProt
- Q14134
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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