XPC 抗体 (AA 146-838)
Quick Overview for XPC 抗体 (AA 146-838) (ABIN7600078)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 146-838
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原理
- Anti-XPC Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-XPC Antibody Picoband® (ABIN7600078). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human XPC recombinant protein (Position: D146-E838).
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亚型
- IgG
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anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 700-940) antibody
XPC 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (C-Term) antibodyXPC 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 141-250) antibodyXPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D11 unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 734-933) antibodyXPC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) (AA 734-933) antibodyXPC 适用: 大鼠 FACS 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibodyXPC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (HRP)XPC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (FITC)XPC 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anantharaman, V., Koonin, E. V., Aravind, L. Peptide-N-glycanases and DNA repair proteins, Xp-C/Rad4, are, respectively, active and inactivated enzymes sharing a common transglutaminase fold. Hum. Molec. Genet. 10: 1627-1630, 2001. 2. Balbo Pogliano, C. B., Gatti, M., Ruthemann, P., Garajova, Z., Penengo, L., Naegeli, H. ASH1L histone methyltransferase regulates the handoff between damage recognition factors in global-genome nucleotide excision repair. Nature Commun. 8: 1333, 2017. 3. Ben Rekaya, M., Messaoud, O., Talmoudi, F., Nouira, S., Ouragini, H., Amouri, A., Boussen, H., Boubaker, S., Mokni, M., Mokthar, I., Abdelhak, S., Zghal, M. High frequency of the V548A fs X572 XPC mutation in Tunisia: implication for molecular diagnosis. J. Hum. Genet. 54: 426-429, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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别名
- XPC
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背景
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Synonyms: Galectin-1, Gal-1, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, S-Lac lectin 1, Lgals1, Gbp,
Tissue Specificity: Widespread, most predominant in spleen, lung and prostate.
Background: Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the XPC gene. The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 106 kDa
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基因ID
- 7508
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UniProt
- Q01831
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途径
- p53 Pathway, DNA Damage Repair
抗原
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