TRAF1 抗体 (AA 14-404)
Quick Overview for TRAF1 抗体 (AA 14-404) (ABIN7600020)
抗原
See all TRAF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-404
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原理
- Anti-TRAF1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TRAF1 Antibody Picoband® (ABIN7600020). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TRAF1 recombinant protein (Position: D14-D404).
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亚型
- IgG
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anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 301-416) antibody
TRAF1 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (C-Term) antibodyVerified TRAF1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 1-416) antibodyTRAF1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 1-416) antibodyTRAF1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 73-219) antibodyTRAF1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TRAF1-2770 unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 131-381) antibodyTRAF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 1-416) antibodyTRAF1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 1-416) antibodyTRAF1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G9-G10 unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (AA 73-219) antibodyTRAF1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TRAF1-3298 unconjugated
anti-TNF Receptor-Associated Factor 1 (TRAF1) (C-Term) antibodyTRAF1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mosialos, G., Birkenbach, M., Yalamanchili, R., VanArsdale, T., Ware, C., Kieff, E. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell 80: 389-399, 1995. 2. Siemienski, K., Peters, N., Scheurich, P., Wajant, H. Organization of the human tumour necrosis factor receptor-associated factor 1 (TRAF1) gene and mapping to chromosome 9q33-34. Gene 195: 35-39, 1997. 3. Tsitsikov, E. N., Laouini, D., Dunn, I. F., Sannikova, T. Y., Davidson, L., Alt, F. W., Geha, R. S. TRAF1 is a negative regulator of TNF signaling: enhanced TNF signaling in TRAF1-deficient mice. Immunity 15: 647-657, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
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别名
- TRAF1
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背景
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Synonyms: KiSS-1 receptor, KiSS-1R, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, hOT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, KISS1R, AXOR12, GPR54
Tissue Specificity: Most highly expressed in the pancreas, placenta and spinal cord, with lower-level of expression in peripheral blood leukocytes, kidney, lung, fetal liver, stomach, small intestine, testes, spleen, thymus, adrenal glands and lymph nodes. In the adult brain, expressed in the superior frontal gyrus, putamen, caudate nucleus, cingulate gyrus, nucleus accumbens, hippocampus, pons and amygdala, as well as the hypothalamus and pituitary. Expression levels are higher in early (7-9 weeks) than term placentas. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells. Expressed at higher levels in first trimester trophoblasts than at term of gestation. Also found in the extravillous trophoblast suggesting endocrine/paracrine activation mechanism.
Background: TRAF1 (TNF Receptor-Associated Factor 1), also called EBI6, is a protein that in humans is encoded by the TRAF1 gene. The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. Siemienski et al. (1997) used fluorescence in situ hybridization to map the TRAF1 gene to 9q33-q34. Mosialos et al. (1995) found that LMP1, the EBV-transforming protein, specifically associates with LAP1 (TRAF3) or EBI6 in B lymphoblasts. LMP1 expression res LAP1 and EBI6 from scattered cytoplasmic structures to LMP1 plasma membrane patches. Both LAP1 and EBI6 associated with the cytoplasmic domain of p80/TNFR2 in vivo.
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分子量
- 46 kDa
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基因ID
- 7185
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UniProt
- Q13077
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途径
- NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
抗原
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