Caspase 9 抗体 (AA 11-120)
Quick Overview for Caspase 9 抗体 (AA 11-120) (ABIN724160)
抗原
See all Caspase 9 (CASP9) 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- AA 11-120
- 
                                            交叉反应
- 小鸡, 犬, 人, 小鼠, 兔, 大鼠
- 
                                            预测反应
- Cow
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human Caspase 9 subunit p35
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 FCM 1:20-100
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
- 
                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 
                                            有效期
- 12 months
 
- 
                                            
- 
    - 
                                            : "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes."    in: PLoS ONE, Vol. 12, Issue 4, pp. e0173469, (2017)         (PubMed).        
 : "TM4SF1 Promotes Proliferation, Invasion, and Metastasis in Human Liver Cancer Cells." in: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).
 : "Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways." in: Heart and vessels, (2016) (PubMed).
 : "Cytotoxicity of pilocarpine to human corneal stromal cells and its underlying cytotoxic mechanisms." in: International journal of ophthalmology, Vol. 9, Issue 4, pp. 505-11, (2016) (PubMed).
 : "C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis." in: Molecular neurobiology, Vol. 49, Issue 2, pp. 1102-16, (2014) (PubMed).
 : "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).
 : "Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], (2014) (PubMed).
 : "Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 1, pp. 28-42, (2013) (PubMed).
 
 
- 
                                            : "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes."    in: PLoS ONE, Vol. 12, Issue 4, pp. e0173469, (2017)         (PubMed).        
- 
    - Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- 
                                            别名
- Caspase 9
- 
                                            背景
- 
                        Synonyms: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9 Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. 
- 
                                            基因ID
- 842
- 
                                            UniProt
- P55211
- 
                                            途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
 抗原
- 
                    
 
                                     
                                     
                                    