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p53 抗体 (Cy3)

The Cy3-conjugated 小鼠 单克隆 anti-p53 antibody (Clone D2F7) (ABIN723369) specifically detects p53 in WB. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN723369
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for p53 抗体 (Cy3) (ABIN723369)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

适用

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人, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This p53 antibody is conjugated to Cy3

应用范围

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Western Blotting (WB)

克隆位点

D2F7
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein G.

    免疫原

    KLH conjugated synthetic peptide derived from human P53(wt-p53)

    亚型

    IgG
  • 应用备注

    IF(IHC-P)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53

    背景

    Synonyms: Widespread p53, Wtp53, Antigen NY-CO-13, Cellular tumor antigen p53, Cys 51 Stop, HGNC11998, LFS1, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, Phosphoprotein p53, TP53, Transformation related protein 53, TRP53, Tumor protein p53, Tumour Protein p53, P53_HUMAN, TP53.

    Background: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

    基因ID

    7157

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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