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Insulin 抗体

This anti-Insulin antibody is a 小鼠 单克隆 antibody detecting Insulin in IHC (p), IF (p) 和 IF (cc). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN722601
发货至: 中国

Quick Overview for Insulin 抗体 (ABIN722601)

抗原

See all Insulin (INS) 抗体
Insulin (INS)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Insulin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

1G11
  • 交叉反应

    纯化方法

    Purified by Protein G.

    免疫原

    Recombinant human Insulin protein

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Zöllner, Jouni, Panzer, Khadour, Janzen, Wesche, Ten Berg, Schellong, Heinken, Greinacher, Bakchoul: "Platelet activation in the presence of neutral protamine Hagedorn insulin: a new feature of antibodies against protamine/heparin complexes." in: Journal of thrombosis and haemostasis : JTH, (2016) (PubMed).

  • 抗原

    Insulin (INS)

    别名

    Insulin

    背景

    Synonyms: ILPR, INS, Insulin A chain, Insulin B chain, Insulin A chain, Insulin precursor, IRDN, Proinsulin, Proinsulin precursor, IDDM2, INS_HUMAN, MODY10.

    Background: Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76 % sequence identity and are 50 % related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.

    基因ID

    3630

    途径

    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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