XPC 抗体 (AA 32-133)
Quick Overview for XPC 抗体 (AA 32-133) (ABIN7539725)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 32-133
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原理
- XPC Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human XPC (AA: 32-133) expressed in mammalian.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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别名
- XPC
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背景
- The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 106 kDa
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UniProt
- Q01831
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途径
- p53 Pathway, DNA Damage Repair
抗原
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