FGFR3 抗体
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北京 101111
Quick Overview for FGFR3 抗体 (ABIN7539297)
抗原
See all FGFR3 抗体片段
适用
宿主
克隆类型
标记
应用范围
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原理
- FGFR-3 neutralizing antibody antibody
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特异性
- Chromosomal location:4p16.3
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纯化方法
- Ion exchange chromatography
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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储存条件
- 4 °C,-20 °C
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储存方法
- Lyophilized samples are stable for up to a year at -20°C. Upon reconstitution, the Fab is stable for up to 1 month at 4°C or up to 1 year at -20°C.
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有效期
- 24 months
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- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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别名
- FGFR-3
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背景
- FGFR3, ACH, CEK2, JTK4, CD333, HSFGFR3EX,Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.
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基因ID
- 2261
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NCBI登录号
- NM_000142, NP_000133
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UniProt
- P22607
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
抗原
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