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CD79a 抗体 (AA 208-222) (FITC)

CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, 犬, Non-Human Primate FACS 宿主: 小鼠 Monoclonal HM47 FITC
产品编号 ABIN7505957
发货至: 中国
  • 抗原 See all CD79a (CD79A) 抗体
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    抗原表位
    • 69
    • 25
    • 10
    • 10
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
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    • 3
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    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-222
    适用
    • 188
    • 97
    • 80
    • 51
    • 50
    • 32
    • 27
    • 25
    • 25
    • 25
    • 15
    • 10
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    • 1
    人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, 犬, Non-Human Primate
    宿主
    • 104
    • 98
    • 1
    小鼠
    克隆类型
    • 120
    • 82
    • 1
    单克隆
    标记
    • 90
    • 18
    • 16
    • 14
    • 14
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    This CD79a antibody is conjugated to FITC
    应用范围
    • 115
    • 97
    • 64
    • 58
    • 45
    • 25
    • 22
    • 15
    • 10
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    原理
    Anti-Hu CD79a FITC
    特异性
    The mouse monoclonal antibody HM47 reacts with intracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.
    纯化方法
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a
    克隆位点
    HM47
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD79A Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    别名
    CD79a (CD79A 产品)
    别名
    CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody
    背景
    CD79a molecule,CD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.,BCR alpha, Ig-alpha, MB-1, IGA
    基因ID
    973
    UniProt
    P11912
    途径
    BCR Signaling
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