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CD79a 抗体 (AA 202-216) (PE)

Name: CD79a 抗体 (AA 202-216) (PE)
Brand: antibodies-online
SKU: ABIN302041
Availability: OutOfStock

CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, Opossum FACS 宿主: 小鼠 Monoclonal HM57 PE

Flow cytometry analysis (intracellular staining) of CD79a with anti-CD79a (HM57) PE (gated on leukemic blast cells) in a patient with childhood B-precursor ALL. (CD79a 抗体 (AA 202-216) (PE))

FACS

Intracellular staining of CD79a with anti-CD79a (HM57) PE(gated on leukemic blast cells) in a patient with childhood B-precursor ALL. (CD79a 抗体 (AA 202-216) (PE))

Intracellular staining of CD79a in human peripheral blood with anti-CD79a (HM57) PE. (CD79a 抗体 (AA 202-216) (PE))

FACS

3 images

(6 references)

产品编号 ABIN302041

发货至: 中国

Datasheet as PDF

抗原 See all CD79a (CD79A) 抗体

CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
抗原表位
68

25

11

10

8

7

7

6

6

5

5

5

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 202-216
适用
188

97

80

51

50

32

27

25

25

25

16

9

5

5

2

1
人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, Opossum
宿主
104

98

1
小鼠
Compatible Secondaries
克隆类型
120

82

1
单克隆
标记
90

17

16

15

14

8

5

5

5

5

5

5

2

1

1

1

1

1

1

1

1

1

1

1
This CD79a antibody is conjugated to PE
应用范围
115

97

64

58

45

25

22

15

10

5

5

3

2

1

1

1

1
Flow Cytometry (FACS)

特异性

The antibody HM57 interacts with intracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.

交叉反应（详细）

Human, Porcine, Mouse, Rat, Bovine, Equine (Horse), Guinea pig, Opossum, Rabbit, Chicken, Other not determined

纯化方法

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

Synthetic peptide corresponding to amino acids 202-216 of human CD79a

克隆位点

HM57

亚型

IgG1

Top Product

Discover our top product CD79A Primary Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 30-193) antibody
CD79A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 FACS, IF, WB, IHC, StM 宿主: 兔 Monoclonal IGA-1790R unconjugated Recombinant Antibody

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 FACS, IF, WB, IHC, StM 宿主: 小鼠 Monoclonal JCB117-HM47-A9 unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-145) antibody
CD79A 适用: 人 IF, WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibody
CD79A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibody
CD79A 适用: 人 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal rIGA-764 unconjugated Recombinant Antibody

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody (FITC)
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, Opossum FACS 宿主: 小鼠 Monoclonal HM57 FITC

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, Opossum FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal HM57 unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222) antibody
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, 犬, Non-Human Primate FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal HM47 unconjugated

anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222) antibody (PE)
CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 马, 兔, 豚鼠, 犬, Non-Human Primate FACS 宿主: 小鼠 Monoclonal HM47 PE

应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.

说明

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
溶解方式

No reconstitution is necessary.

缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.
Avoid prolonged exposure to light.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Faldyna, Samankova, Leva, Cerny, Oujezdska, Rehakova, Sinkora: "Cross-reactive anti-human monoclonal antibodies as a tool for B-cell identification in dogs and pigs." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 56-62, (2007) (PubMed).

Mason, Cordell, Brown, Borst, Jones, Pulford, Jaffe, Ralfkiaer, Dallenbach, Stein: "CD79a: a novel marker for B-cell neoplasms in routinely processed tissue samples." in: Blood, Vol. 86, Issue 4, pp. 1453-9, (1995) (PubMed).

Jones, Cordell, Beyers, Tse, Mason: "Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5429-35, (1993) (PubMed).

Mason, van Noesel, Cordell, Comans-Bitter, Micklem, Tse, van Lier, van Dongen: "The B29 and mb-1 polypeptides are differentially expressed during human B cell differentiation." in: European journal of immunology, Vol. 22, Issue 10, pp. 2753-6, (1992) (PubMed).

Mason, Cordell, Tse, van Dongen, van Noesel, Micklem, Pulford, Valensi, Comans-Bitter, Borst: "The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, (1991) (PubMed).

van Noesel, van Lier, Cordell, Tse, van Schijndel, de Vries, Mason, Borst: "The membrane IgM-associated heterodimer on human B cells is a newly defined B cell antigen that contains the protein product of the mb-1 gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 11, pp. 3881-8, (1991) (PubMed).
抗原

CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

别名

CD79a (CD79A 产品)

别名

CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody

背景

CD79a molecule,CD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.,BCR alpha, Ig-alpha, MB-1, IGA

基因ID

973

UniProt

P11912

途径

BCR Signaling