XPC 抗体
Quick Overview for XPC 抗体 (ABIN7469197)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Human XPC
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交叉反应
- 人
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纯化方法
- Affinity purified with antigen.
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免疫原
- Peptide conjugated to a carrier protein
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亚型
- IgG
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应用备注
- Optimal dilutions/concentrations should be determined by the researcher.
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说明
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Positive Control: HeLa , *GM00637
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS pH 7.2, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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别名
- XPC complex subunit, DNA damage recognition and repair factor
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背景
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Synonyms: XPC complex subunit, DNA damage recognition and repair factor , RAD4 , XP3 , XPCC , p125
Background: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
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分子量
- 106 kDa
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基因ID
- 7508
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UniProt
- Q01831
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途径
- p53 Pathway, DNA Damage Repair
抗原
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