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Retinoblastoma Binding Protein 8 抗体

The 小鼠 单克隆 anti-Retinoblastoma Binding Protein 8 antibody (Clone 1-90E-09) (ABIN7468880) specifically detects Retinoblastoma Binding Protein 8 in WB, IP, ICC, IF, PLA 和 ChIP. The antibody is reactive with 人 samples.
产品编号 ABIN7468880
发货至: 中国
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Quick Overview for Retinoblastoma Binding Protein 8 抗体 (ABIN7468880)

抗原

See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
Retinoblastoma Binding Protein 8 (RBBP8)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Retinoblastoma Binding Protein 8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Proximity Ligation Assay (PLA), Chromatin Immunoprecipitation (ChIP)

质量等级

KO Validated

克隆位点

1-90E-09
  • 交叉反应

    人, 小鼠

    纯化方法

    Protein G purified

    免疫原

    Human CtIP

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:1000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, No preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Retinoblastoma Binding Protein 8 (RBBP8)

    别名

    RB binding protein 8, endonuclease

    背景

    Synonyms: RB binding protein 8, endonuclease , COM1 , CTIP , JWDS , RIM , SAE2 , SCKL2

    Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]

    分子量

    102 kDa

    基因ID

    5932

    UniProt

    Q99708

    途径

    Cell Division Cycle, DNA Damage Repair
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