Retinoblastoma Binding Protein 8 抗体
Quick Overview for Retinoblastoma Binding Protein 8 抗体 (ABIN7468880)
抗原
See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
交叉反应
- 人, 小鼠
-
纯化方法
- Protein G purified
-
免疫原
- Human CtIP
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1:500-1:1000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Validation: KO/KD, Orthogonal
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1XPBS pH 7, 20 % Glycerol, No preservative
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- Retinoblastoma Binding Protein 8 (RBBP8)
-
别名
- RB binding protein 8, endonuclease
-
背景
-
Synonyms: RB binding protein 8, endonuclease , COM1 , CTIP , JWDS , RIM , SAE2 , SCKL2
Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
-
分子量
- 102 kDa
-
基因ID
- 5932
-
UniProt
- Q99708
-
途径
- Cell Division Cycle, DNA Damage Repair
抗原
-